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It is of particular importance to note the following fact. Malignant changes, tumors, develop and survive predominantly in an acidic environment. The acidic environment is the basis for the development of many types of microorganisms, especially all types of fungi. Fungi are an excellent basis for the development of malignant tumors, and in this way a vicious circle is created. Disorder of acid-base balance in the body can also cause life-threatening changes, especially if the concentration of H + ions increases significantly (pH less than 7). Then an acidotic coma can occur.

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Moreover, most people are irregular and do not have bowel movements every day or the same number of bowel movements each day. Medically speaking, constipation usually is defined as fewer than three bowel movements per week. Severe constipation is defined as less than one bowel movement per week.

Emotional effects include depression, anger, anxiety, and fear of re-injury. This fear may hinder a person's ability to return to normal work or leisure activities.

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